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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K7
All Species:
14.85
Human Site:
Y405
Identified Species:
29.7
UniProt:
O43318
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43318
NP_003179.1
606
67196
Y405
R
I
A
A
T
T
A
Y
S
K
P
K
R
G
H
Chimpanzee
Pan troglodytes
XP_001160138
472
51727
I283
S
M
E
E
I
V
K
I
M
T
H
L
M
R
Y
Rhesus Macaque
Macaca mulatta
XP_001099744
609
67549
Y405
R
I
A
A
T
T
A
Y
S
K
P
K
R
G
H
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q62073
579
64209
S378
S
R
G
S
S
V
E
S
L
P
P
T
S
E
G
Rat
Rattus norvegicus
P0C8E4
606
67182
Y405
R
I
V
A
T
T
A
Y
T
K
P
K
R
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507638
595
66386
Y394
R
I
A
A
T
T
A
Y
S
K
P
K
R
G
H
Chicken
Gallus gallus
XP_001233491
604
67342
R395
D
M
S
E
M
E
A
R
I
P
S
T
T
A
Y
Frog
Xenopus laevis
Q7T2V3
1005
111856
T546
T
P
V
D
G
S
K
T
W
G
R
S
S
V
L
Zebra Danio
Brachydanio rerio
NP_001018586
544
61104
S354
V
E
S
L
P
G
R
S
H
F
Q
P
S
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3Q6
678
75656
N388
E
E
S
N
E
S
R
N
D
S
F
N
L
T
S
Honey Bee
Apis mellifera
XP_397248
510
58111
A321
S
E
I
N
G
Y
A
A
N
G
T
I
K
I
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795629
463
51420
V274
V
D
L
L
D
L
R
V
D
N
D
N
S
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.4
99.5
N.A.
N.A.
95
99
N.A.
91.4
91.7
21.9
70.6
N.A.
34.5
41.4
N.A.
39.9
Protein Similarity:
100
75.7
99.5
N.A.
N.A.
95
99.3
N.A.
93.7
93.7
35.7
77.8
N.A.
52.2
58.7
N.A.
51.4
P-Site Identity:
100
0
100
N.A.
N.A.
6.6
86.6
N.A.
100
6.6
0
0
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
13.3
100
N.A.
N.A.
20
93.3
N.A.
100
26.6
6.6
6.6
N.A.
13.3
26.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
34
0
0
50
9
0
0
0
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
0
9
9
0
0
0
17
0
9
0
0
0
9
% D
% Glu:
9
25
9
17
9
9
9
0
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% F
% Gly:
0
0
9
0
17
9
0
0
0
17
0
0
0
34
9
% G
% His:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
34
% H
% Ile:
0
34
9
0
9
0
0
9
9
0
0
9
0
9
0
% I
% Lys:
0
0
0
0
0
0
17
0
0
34
0
34
9
0
9
% K
% Leu:
0
0
9
17
0
9
0
0
9
0
0
9
9
0
9
% L
% Met:
0
17
0
0
9
0
0
0
9
0
0
0
9
0
0
% M
% Asn:
0
0
0
17
0
0
0
9
9
9
0
17
0
0
9
% N
% Pro:
0
9
0
0
9
0
0
0
0
17
42
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
34
9
0
0
0
0
25
9
0
0
9
0
34
9
0
% R
% Ser:
25
0
25
9
9
17
0
17
25
9
9
9
34
9
9
% S
% Thr:
9
0
0
0
34
34
0
9
9
9
9
17
9
9
0
% T
% Val:
17
0
17
0
0
17
0
9
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
34
0
0
0
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _